- "As an infectious disease researcher, I need to identify the three most prevalent infectious diseases currently impacting sub-Saharan Africa. Please find relevant proteins for these diseases, analyze the binding sites of these proteins, and compile all findings into a comparison table. Include cit
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"As an infectious disease researcher, I need to identify the three most prevalent infectious diseases currently impacting sub-Saharan Africa. Please find relevant proteins for these diseases, analyze the binding sites of these proteins, and compile all findings into a comparison table. Include citations to relevant literature where possible."
"I'm a neurodegenerative disease specialist examining potential drug targets. Please identify key proteins involved in Alzheimer's, Parkinson's, and Huntington's diseases. For each disease, analyze the binding sites of the most promising therapeutic target protein and create a detailed report highlighting similarities and differences that could inform drug development. Please cite relevant research papers throughout your analysis."
"As a cancer immunotherapy researcher, I'm investigating checkpoint inhibitors. Identify the three most studied checkpoint proteins in cancer therapy, examine their binding interfaces with antibodies, and present a structural analysis of how these interactions disrupt immune evasion by tumors. Include citations to seminal papers and recent findings where appropriate."
"I'm developing antivirals against emerging threats. Please identify three RNA viruses with pandemic potential, determine their essential protease structures, analyze the conserved features of their active sites, and suggest possible broad-spectrum inhibitor design strategies based on structural commonalities. Cite relevant literature for each virus and for your structural insights."
"As an antibiotic resistance researcher, I need to understand structural adaptations in bacterial proteins. Identify three beta-lactamase enzymes from different resistant bacterial strains, analyze their active sites, and create a visual comparison highlighting the structural differences that confer resistance to current antibiotics. Please support your analysis with citations to published structural and biochemical studies."